Director, Regulatory Strategy (Medical Devices)

Lakewood, CO

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Type: Direct-Hire

Experience: 0

Category: Scientific & Clinical

Contractor Work Model: Hybrid

Brand: Joulé

Compensation Range: 195500.00 - 245600.00

Job ID: 346366

Date Posted: 02/13/2026

Shortcut: http://jobs.systemone.com/CljWqP


Director of Regulatory Strategy (Medical Devices)
Medical Device | Global Scope | Denver Metro (Hybrid)
Compensation: $195,000–$245,000 base + 30% target bonus
(Compensation aligned to experience, scope, and market benchmarks.)


The Opportunity
A well-established and growth-oriented medical device organization is seeking a strategic regulatory leader to guide global regulatory affairs and labeling strategy across a diverse product portfolio. This role offers the opportunity to shape regulatory direction at the executive level while driving product approvals, lifecycle management, and global compliance initiatives.
This is a highly visible leadership position supporting innovation from early development through commercialization and post-market compliance.

Location Requirement: Candidates must reside in the Denver metro area to support a hybrid work model.

What You’ll Lead
  • Define and execute global regulatory strategy aligned to business objectives.
  • Provide executive-level regulatory guidance for new product introductions and existing commercial portfolios.
  • Oversee global labeling strategy and ensure alignment with evolving regulatory standards.
  • Serve as the primary liaison to regulatory authorities worldwide.
  • Direct major submissions including 510(k), PMA, IDE, CE Mark technical documentation, and applicable pharmaceutical filings (NDA/ANDA).
  • Champion compliance programs including UDI, state licensing, regulatory operations, and broader quality initiatives.
  • Anticipate regulatory risks and proactively develop mitigation strategies.
  • Guide cross-functional teams across R&D, Clinical, Quality, Legal, Manufacturing, and Commercial.
  • Represent regulatory strategy at management reviews and executive forums.
  • Lead, mentor, and develop a high-performing regulatory team.
  • Monitor global regulatory trends and participate in industry engagement to proactively influence change.
Ideal Background
We’re seeking a regulatory executive who combines strategic vision with operational depth.
Required Experience:
  • 10+ years of progressive regulatory affairs experience within medical devices (combination product experience strongly preferred).
  • Demonstrated success leading global regulatory submissions and securing approvals for complex technologies.
  • Experience interacting directly with regulatory agencies in the U.S. and internationally.
  • Strong background in global labeling oversight.
  • 5+ years of people leadership experience, including managing senior-level professionals.
  • Expertise in regulatory compliance across U.S., EU, Canada, and other international markets.
Preferred Experience:
  • Experience with sterile disposables and/or electro-mechanical devices with embedded software.
  • Exposure to drug/device combination products.
  • Experience collaborating closely with clinical teams throughout trial phases.
  • Background supporting or partnering closely with Quality Management Systems.
  • Regulatory certification (e.g., RAC) is a plus.
Leadership Profile
Successful candidates will demonstrate:
  • Executive-level strategic thinking with the ability to translate complex regulations into practical business solutions.
  • Confidence representing innovative technologies before regulatory bodies.
  • Strong influence skills across senior leadership and cross-functional stakeholders.
  • The ability to build a culture of quality and regulatory excellence.
  • Comfort operating in environments where regulatory pathways may require creative and forward-thinking strategy.
Additional Details
  • Hybrid schedule (Denver metro required).
  • 10–15% international travel.
  • Occasional off-hours engagement consistent with executive-level responsibilities.



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