Senior Associate Scientist – Vector Process Development (Upstream)
Cambridge, MA
Experience: 0
Category: Scientific & Clinical
Contractor Work Model: Onsite
Brand: Joulé
Compensation Range: 45.00 - 55.00 Per Hour
Job ID: 346695
Date Posted: 02/23/2026
Shortcut: http://jobs.systemone.com/Q61vhV
Job Title: Senior Associate Scientist Vector Process Development
Location: Cambridge, Massachusetts
Type: Contract
Compensation: $45 - $55 hourly
Contractor Work Model: 4 days onsite, 1 day remote
Hours: 8 AM- 5 PM M-F
Responsibilities:
Responsible for the development of robust, efficient, scalable and transferable lentiviral vector (LVV) manufacturing for early and late-stage cell therapy programs, for both ex-vivo and in-vivo delivery approaches. This role will have the opportunity to directly support current pipeline programs in process development and CMC activities, as well as drive ground breaking technology development of next generation vector processes.
- Complete routine PD-grade viral vector production operations at both bench scale and pilot scale, including but not limited to media preparation, culture initiation, seed train maintenance and bioreactor operations, to support process development studies and material generation for pre-clinical programs.
- Perform viral vector production experiments to assess the impact of process changes and new technologies to drive critical innovation projects for next generation LVV production processes.
- Develop experimental plans, interpret scientific results, and provide statistical analysis where appropriate.
- Perform general laboratory tasks, including maintenance of equipment and inventory.
- Support technology transfer activities to manufacturing partners as an upstream SME.
- Generate, manage, evaluate, and maintain critical data in an organized way, including lab notebook maintenance with good documentation practices.
- BS/MS in Bioengineering, Chemical engineering, Biology, Cell Biology or related biological sciences
- 2+ years (MS), or 4+ years (BS) of proven experience in biotechnology or pharmaceutical industry.
- Understanding of cell biology and hands-on experience with mammalian cell culture is required.
- Experience with vector process development and manufacturing is preferred.
- Experience with bioreactors, control software, and process analytical technology is strongly preferred.
- General knowledge of process development and pharmaceutical manufacturing is helpful.
- Experience with scale-up and pilot plant operations is a plus.
System One, and its subsidiaries including Joulé, ALTA IT Services, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.
System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.
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Ref: #558-Scientific
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