Downstream Purification Scientist
Boston, MA
Experience: 0
Category: Scientific & Clinical
Contractor Work Model: Onsite
Brand: Joulé
Compensation Range: 40.62 - 47.78 Per Hour
Job ID: 350520
Date Posted: 05/11/2026
Shortcut: http://jobs.systemone.com/enrY0j
Job Title: Downstream Purification Scientist
Location: Boston, MA
Type: Contract
Compensation: $40.62 - 47.78/hr
Work Model: Onsite – onsite
Responsibilities
- Execute purification processes including CsCl density gradient ultracentrifugation, affinity chromatography (e.g., AVB, CaptureSelect), ion-exchange chromatography (AEX, CEX), and other polishing steps.
- Operate AKTA systems (Avant, Pure, or Pilot) for small- to large-scale purification runs.
- Perform TFF operations for buffer exchange and concentration of intermediate or final products.
- Support experimental design, data collection, and documentation following established procedures and GMP/GLP best practices.
- Assist in troubleshooting and optimization of purification processes.
- Analyze in-process and purified samples using relevant analytical methods (e.g., UV, SDS-PAGE, ddPCR, ELISA, or HPLC).
- Collaborate cross-functionally with upstream, analytical, and manufacturing teams.
- Maintain lab equipment, manage buffers and column inventory, and ensure compliance with safety and documentation standards.
-
Education: Master’s degree in biology, biochemistry, chemical engineering, biotechnology, or related field.
-
Experience: Minimum 2 years of hands-on purification experience in an academic or industry setting.
- Experience operating AKTA purification systems is preferred
- Ability to perform TFF operations and analytical sample testing
- Excellent documentation and GMP/GLP compliance skills
- Effective communication and teamwork skills
- Bachelor’s degree in Life Sciences, Biochemistry, Biotechnology, or related discipline
System One, and its subsidiaries including Joulé and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.
System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.
Ref: #558-Scientific
-
Scientist
Tarrytown, NY
Job Title: Scientist Location: Tarrytown, NY Type: Contract Compensation: $55.00 - $60.00 Contractor Work Model: Onsite – onsite Hours: 8 AM- 5 PM M-F Responsibilities Design, plan, and execute in vitro and in vivo studies using cell lines and mouse mo...
Date Posted: 05/11/2026 Recommended
-
Manufacturing Associate (Downstream)
Pennington, New Jersey
Job Title: Manufacturing Associate (Upstream & Downstream) Location: Pennington, New Jersey Type: Contract Compensation: $25.00–$32.00 per hour Contractor Work Model: Onsite Hours: 40.0 hours per week 8a-5p Responsibilities Support both Upstream and Do...
Date Posted: 05/13/2026 Recommended
-
Scientist II
Ridgefield, CT
Job Title: Scientist II Location: Ridgefield, CT Type: Contract Compensation: $30 -$40.00 Contractor Work Model: Onsite Hours: 40 hrs/week Overview Leading pharmaceutical company looking for an experienced Scientist II. Ideal candidates should have a M...
Date Posted: 04/22/2026 Recommended
-
Scientist 1
Rockville, MD
Job Title: Scientist Location: Rockville, MD, United States Type: Contract Schedule: Monday - Friday Day Hours Overview Biopharmaceutical company in Rockville, MD is seeking a Scientist to join their team. Responsibilities Perform cell culture media pr...
Date Posted: 04/30/2026 Recommended
-
Mass Spectrometry Scientist - REACH Scientist
Naugatuck, Connecticut
Job Title: Mass Spectrometry Scientist – REACH Scientist Location: Naugatuck, Connecticut Hours/Schedule: M-F, 8 AM – 5 PM Type: Contract Overview Our client, a global chemical manufacturer, is seeking a Mass Spectrometry Scientist – REACH Scientist to...
Date Posted: 03/30/2026 Recommended
-
AI/ Data Scientist
NA, VA
Job Title: AI/ Data Scientist Location: Remote Security Clearance: due to government requirement: U.S. Citizenship required and ability to obtain and maintain a Public Trust clearance If interested reach out directly to kimberly.spicer@systemone.com Re...
Date Posted: 04/17/2026 Recommended
-
Associate Scientist Neuroscience
Tarrytown, NY
Job Title: Associate Scientist Neuroscience Location: Tarrytown, NY Type: Contract Compensation: $38.00 - $45.00 per hour Contractor Work Model: Onsite Hours: 8 AM - 5 PM M-F Responsibilities Support preclinical research in the Neurotherapeutics area w...
Date Posted: 03/16/2026 Recommended
-
Traveling MEP Manager
Boston, Massachusetts
Job Title: M/E/P Manager Location: Saratoga Springs, NY Employment Type: Full-Time Department: Mechanical / Electrical / Plumbing (M/E/P) Salary: $120k-$150k + $9,300 monthly travel stipend Overview System One is seeking an experienced M/E/P Manager to...
Date Posted: 04/28/2026 Recommended
-
Senior Scientist, Medical Affairs COE
Plainsboro, NJ
Job Title: Senior Scientist, Medical Affairs Location: Plainsboro, NJ Type: Contract Contractor Work Model: Onsite – onsite Hours: 40.0 Leading Pharmaceutical Company located in NJ is hiring a Senior Scientist, Medical Affairs w/ 3+ years industry expe...
Date Posted: 04/27/2026 Recommended
-
Animal Technician
Boston, Massachusetts
Job Title: Animal Technician Location: Boston, Massachusetts Type: Contract To Hire Compensation: $21 hourly Contractor Work Model: Onsite Hours: 7:00 to 3:30pm Requirements Minimum of High School Diploma Experience with care of animals (mice and rats)...
Date Posted: 04/29/2026 Recommended
-
Analytical Chemist / Senior Lab Technician
Pleasanton, California
Job Title: Analytical Chemist / Senior Lab Technician Location: Pleasanton, California Hours / Schedule: 8am - 5pm, Monday - Friday, Onsite Type: Contract Compensation: up to $32 per hour Responsibilities Perform reliable sample preparation and analyti...
Date Posted: 04/17/2026 Recommended
-
Associate Scientist Immunology & Inflammation
Tarrytown, NY
Job Title: Associate Scientist Immunology & Inflammation Location: Tarrytown, NY Type: Contract Compensation: $40.00 - $45.00 per hour Contractor Work Model: Onsite Hours: 8 AM - 5 PM Responsibilities Support respiratory and inflammatory disease resear...
Date Posted: 04/21/2026 Recommended
-
Manufacturing Associate
Novato, CA
Job Title: Manufacturing Associate Location: Novato, CA Type: Contract Compensation: $28.00 Contractor Work Model: Onsite – onsite Hours: Thursday - Saturday with Alternating Wednesdays (6am to 7pm) / Rotating 12hour shift Overview Leading biotechnolog...
Date Posted: 05/13/2026 Recommended
-
Manufacturing Associate
Novato, CA
Job Title: Manufacturing Associate Location: Novato, CA Type: Contract Compensation: $28.00 + shift differential Contractor Work Model: Onsite – onsite Hours: Sunday- Tuesday, alternating Wednesdays from 6am-7pm Overview Leading biotechnology company l...
Date Posted: 05/14/2026 Recommended
-
Manufacturing Associate
Novato, CA
Job Title: Manufacturing Associate Location: Novato, CA Type: Contract Compensation: $28.00/hr + shift differential Contractor Work Model: Onsite – onsite Hours: Alternating Saturdays /Sundays to Tuesdays from 6pm to 7 am Overview Leading biotechnology...
Date Posted: 05/13/2026 Recommended
-
Senior Associate Scientist Immunology & Inflammation
Tarrytown, NY
Job Title: Senior Associate Scientist Immunology & Inflammation Location: Tarrytown, NY Type: Contract Compensation: $45.00 - $55.00 Contractor Work Model: on sight Hours: 8 AM - 5 PM M-F Responsibilities Design, plan, and perform in vivo studies using...
Date Posted: 04/22/2026 Recommended
-
Manufacturing Associate
Novato, CA
Job Title: Manufacturing Associate Location: Novato CA 94949 Type: Contract Compensation: $28.00 base with shift differential Contractor Work Model: Onsite Hours: Shift is alternating Saturdays, Sunday-Tuesday (6pm to 7am) Overview Leading biotechnolog...
Date Posted: 05/08/2026 Recommended
-
Manufacturing Associate
Novato, CA
Job Title: Manufacturing Associate Location: Novato, CA Hours/Schedule: Alternating Saturdays, Sunday–Tuesday, 6:00 PM – 7:00 AM Compensation: $25-28/hr depending on qualifications Type: 6 month contract Overview The Manufacturing Associate supports co...
Date Posted: 03/17/2026 Recommended
-
Research Data Scientist
Pittsburgh, Pennsylvania
Title: Research Data Scientist Location: Onsite, Pittsburgh, PA 15213 Type: Direct-Hire/Permanent Hours: Standard business hours Start: May Overview: Join a cutting-edge lab to discover novel therapeutics that is seeking a highly motivated Data Scienti...
Date Posted: 04/30/2026 Recommended
-
Manufacturing Technician I
Fremont, CA
Job Title: Manufacturing Technician I Location: Fremont, CA Type: Contract Compensation: $20.66 Contractor Work Model: Onsite Hours: Sun-Wed Days - 38 Hours/week Sun-Tues 3PM-1:30AM Wed 3PM-11:30PM Overview Leading pharmaceutical company looking for an...
Date Posted: 04/28/2026 Recommended
-
Microbiology Lab Technician
Elizabeth, New Jersey
Job Title: Microbiology Lab Technician Location: Elizabeth, New Jersey Type: Contract To Hire Compensation: $23.00 per hour Contractor Work Model: Onsite Hours: 6:00 AM – 2:30 PM (must be flexible to work additional or earlier hours when required) Resp...
Date Posted: 03/31/2026 Recommended
-
Manufacturing Associate
Novato, CA
Job Title: Manufacturing Associate Location: Novato, CA 94949 Type: Contract Compensation: $28.00 per hour with shift differential Contractor Work Model: Onsite Hours: Sunday – Tuesday 6:00 p.m. - 7:00 a.m., with alternating Saturdays Overview Leading ...
Date Posted: 04/13/2026 Recommended
-
Sr Research Associate II
Novato, CA
Job Title: Sr Research Associate II Location: Novato, CA Type: Contract Compensation: $40-$47.10/hr Contractor Work Model: Onsite with occasional evening or weekend hours expected Hours: Monday-Friday 8am to 5pm Overview Leading pharmaceutical company ...
Date Posted: 05/14/2026 Recommended
-
Construction Estimator (Drywall & Interior Finishes)
Boston, Massachusetts
Job Title: Construction Estimator (Drywall & Interior Finishes) Location: Boston, MA Job Type: Full-Time Build Your Career with a Team That’s Growing Fast We’re looking for a driven Construction Estimator to join our team and play a key role in deliver...
Date Posted: 05/08/2026 Recommended
-
Warehouse Inventory Technician
Harleysville, PA
Job Title: Warehouse Inventory Technician Location: Harleysville, PA Schedule: Monday-Friday 9am-1pm Pay Rate: $20-25hr Type: Contract Responsibilities: Receive pharmaceutical products arriving on site. Verify material against supplier packing list. Co...
Date Posted: 05/11/2026 Recommended
-
Director, Project QA Compliance (PERM)
Lake Forest, Illinois
Job Title: Director, Project QA Compliance (PERM) Location: Lake Forest, Illinois OR Morristown, NJ Type: Direct Hire Full Time permanent direct with client Compensation: $150,000 - $190,000 Work Model: Hybrid – onsite Tues and Thursday Hours: 40.0 Thi...
Date Posted: 05/13/2026 Recommended
-
Document Controller
Indianapolis, IN
Job Title: Document Controller Location: Indianapolis, IN Hours: Mon - Fri 8am - 5pm, onsite Compensation: $34.94 - $41.11/hr Type: Contract, Potential for extension or conversion to permanent Responsibilities Owns and manages the end-to-end document c...
Date Posted: 03/25/2026 Recommended
-
Food Safety & QA Specialist
Monroe, NJ
Job Title: Food Safety & QA Specialist Location: Monroe, NJ Type: Direct Hire Compensation: $50000 - $60000 annually Contractor Work Model: Onsite Hours: 8 AM- 5 Pm M-F Responsibilities: Primarily focus on the implementation and maintenance of food saf...
Date Posted: 05/06/2026 Recommended
-
Packaging Associate II - 1st Shift
Macungie, PA
Job Title: Packaging Associate II - 1st Shift Location: Macungie, PA Type: Contract To Hire Compensation: $19.00 Hours: 7:00AM-3:00PM, M-F Overview Established and growing pharmaceutical manufacturing company is seeking to add quality minded packaging ...
Date Posted: 04/22/2026 Recommended
-
Sr Study Specialist
San Rafael, CA
Job Title: Sr Study Specialist Location: San Rafael, CA Type: Contract Compensation: $50 - $58/hour Contractor Work Model: Hybrid Hours: 40.0 Responsibilities Oversee various aspects of clinical study management, including documentation development, si...
Date Posted: 04/17/2026 Recommended