Title: Lead Engineer
Location: Onsite, Pittsburgh, PA 15213
Type: Direct-Hire/Permanent
Hours: Standard business hours
Start: May
Overview:
Join a cutting-edge lab to discover novel therapeutics that are seeking a highly motivated Lead Engineer to support the design, development, integration, and optimization of advanced engineering systems used in complex experimental environments. This role combines device development, fluidic and instrumentation system integration, and process optimization to enable reliable, reproducible, and scalable experimental platforms. The position will contribute to both early-stage prototyping and system-level implementation across multidisciplinary applications.
Responsibilities:

• Design, prototype, and refine devices, components, and system architectures for experimental platforms
• Develop and optimize fabrication, assembly, and integration processes to ensure quality, consistency, and scalability
• Design and implement fluidic systems, including flow control networks, pumps, valves, and routing architectures
• Support development of controlled system environments (e.g., airflow, fluid flow, or dynamic operating conditions)
• Integrate mechanical, fluidic, and instrumentation systems into cohesive, multi-component platforms
• Perform system testing, validation, and performance characterization to ensure reliability and reproducibility
• Troubleshoot technical issues and implement solutions to improve system robustness and efficiency
• Contribute to material selection, manufacturing methods, and design-for-manufacturing strategies
• Maintain detailed documentation including design specifications, system configurations, SOPs, and validation data
• Collaborate with cross-functional teams to align engineering solutions with application and operational needs
• Support preparation of technical reports, documentation, and project deliverables

Requirements:

• Bachelor’s degree in Engineering (Mechanical, Biomedical, Electrical, Systems, or related field)
• Minimum of 3+ years of experience in engineering design, system integration, or experimental platform development
• Experience with prototyping, hardware systems, or device development
• Experience with fluid systems, instrumentation, or process control environments
• Strong analytical, troubleshooting, and problem-solving skills
• Ability to work effectively in multidisciplinary teams

Preferred Qualifications

• Advanced degree (Master’s or Ph.D.) in a relevant engineering discipline
• Experience with complex, multi-component system integration
• Familiarity with fabrication techniques (e.g., precision machining, molding, or small-scale device manufacturing)
• Experience with fluid handling systems, microfluidics, or flow control applications
• Experience with sensors, data acquisition systems, or automated control platforms
• Knowledge of design-for-manufacturing and scalability principles
• Experience working in regulated or controlled environments
• Experience at the interface of engineering and biological or experimental systems

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Ref: #558-Scientific