Lead System Engineer

Pittsburgh, Pennsylvania

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Type: Direct-Hire

Experience: 3

Education: BS

Category: Scientific & Clinical

Contractor Work Model: Onsite

Brand: Joulé

Job ID: 349096

Date Posted: 05/26/2026

Shortcut: http://jobs.systemone.com/3KpMhV


Title: Lead Design Engineer
Location: Onsite, Pittsburgh, PA 15213
Type: Direct-Hire/Permanent
Hours: Standard business hours
Start: May
Overview: Join a cutting-edge lab to discover novel therapeutics that are seeking a highly motivated Lead Engineer to support the development, integration, and operation of advanced aerosol delivery, sensing, and exposure systems for human-relevant experimental platforms. This role focuses on ensuring precise, reproducible generation and delivery of airborne agents, as well as integration of instrumentation and multi-system platforms to enable controlled and standardized experimental workflows. The position will contribute to system optimization, performance validation, and operational readiness in complex laboratory environments.

Responsibilities:

  • Design, prototype, and refine biomedical devices and components supporting advanced experimental system
  • Develop and optimize fabrication processes to ensure consistency, quality, and scalability
  • Contribute to selection and evaluation of materials, fabrication methods, and assembly workflows
  • Perform testing and validation of device performance, including durability, reproducibility, and functional integrity
  • Collaborate with scientific and engineering teams to align device design with experimental requirements
  • Maintain documentation related to design iterations, fabrication processes, and quality control
  • Troubleshoot device-related issues and implement design improvements
  • Support coordination of engineering activities across multidisciplinary teams and contribute to project execution
  • Contribute to preparation of technical documentation, reports, and related materials

Requirements:

  • Bachelor’s degree in Biomedical Engineering, Mechanical Engineering, Electrical / System Engineering, or a related field
  • Minimum of 3 years of relevant experience in device design, prototyping, or fabrication
  • Experience with engineering design tools (e.g., CAD software)
  • Strong problem-solving skills and attention to detail
  • Ability to work effectively in multidisciplinary research and engineering environments

Preferred Qualifications

  • Master’s or Ph.D. in a relevant engineering discipline
  • Experience with fabrication of small-scale or precision-engineered devices, including Organs-on-Chips, injection molding, and CNC milling
  • Familiarity with polymer-based materials and manufacturing processes
  • Experience with iterative prototyping and design-for-manufacturing principles
  • Experience working at the interface of engineering and biological systems

#M3
#LI-DS2
Ref: #558-Scientific

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