OMICS Laboratory Lead/Manager II
Pittsburgh, PA
Experience: 2
Category: Scientific & Clinical
Contractor Work Model: Onsite
Brand: Joulé
Job ID: 346242
Date Posted: 02/12/2026
Shortcut: http://jobs.systemone.com/H7dh2c
Title: OMICS Laboratory Manager II
Location: Onsite, Pittsburgh, PA 15219
Type: 6-month contract to hire
Hours: 8AM-5PM
Start: Immediately
Overview:
Join as a Laboratory Manager II to monitor personnel and workflow in the area. Track and monitor QA/QC in conjunction with other laboratory leadership. Oversee laboratory throughput metrics and workflow optimization, ensuring balanced workloads, adherence to deadlines, and high data fidelity under time-sensitive conditions.
Responsibilities
- Perform clinical testing in accordance with established SOPs and maintain oversight of all clinical testing. Maintain clinical workflow to meet established quality and turnaround time (TAT) goals, including managing technologists and bench schedules and tracking case status (STATs, special requests, etc.).
- Monitor personnel and workflow in the area while tracking QA/QC in collaboration with laboratory leadership. Maintain all QA documentation, including reagent lot tracking, in-use/out-of-use dates, expiration dates, exception logs with corrective actions, and QA reports.
- Maintain competency across all benches and rotate regularly through clinical workflows. Step in to support clinical work when needed and troubleshoot problematic cases, including determining when to repeat or cancel testing.
- Serve as the point person for vendor communication regarding instrument or software issues. Update SOPs as needed to ensure accurate and current documentation.
- With guidance from laboratory leadership and the Medical Director, oversee supplemental validations and procedural changes. Document validations, compile supporting data, and oversee training and cross-training of technologists.
- Monitor and assess technologist competency in compliance with CAP and other regulatory standards. Oversee proficiency testing, track concordance, and document results appropriately.
- Support inspection readiness in collaboration with QA, lab leadership, and the Medical Director. Complete performance reviews for Molecular Genomic Specialists.
- Monitor and approve reagent and supply orders and act as a liaison between technologists and leadership regarding daily workflow updates.
- Track technologist indirect hours (MRS) and collaborate with leadership on development projects, validations, and implementation strategies.
- Maintain ongoing technical and professional development through seminars, webinars, and educational activities.
- Oversee sample triage, barcoding, and data integrity across omics workflows. Ensure CAP/CLIA-compliant sample tracking, storage, and LIMS documentation across genomic, proteomic, metabolomic, and lipidomic assays.
- Coordinate operation, scheduling, and maintenance of high-throughput automation platforms (Eppendorf, Tecan, Hamilton) and analytical instruments (Orbitrap Exploris, Stellar, SomaLogic, iScan).
- Provide mentorship and cross-training on multi-omics preparation, instrument workflows, and data tracking protocols to ensure consistency and scalability.
- Lead validation and process harmonization for new assays and collaborate with QA and regulatory teams to maintain CAP/CLIA readiness and audit documentation.
- Oversee laboratory throughput metrics and workflow optimization to ensure balanced workloads, deadline adherence, and high data fidelity in time-sensitive environments.
- Bachelor’s degree required
- Minimum of 3 years of relevant experience in a high-volume, complex clinical or research laboratory setting
- Advanced Excel skills
- Proficient in molecular biology techniques, including Illumina NGS Next-Generation Sequencing, PCR, library preparation, and barcoding
- Troubleshooting, mentoring and QC review experience
- Experience with laboratory automation and robotic systems, such as Hamilton instruments and automated liquid handlers
System One, and its subsidiaries including Joulé, ALTA IT Services, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.
System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.
#M3
Ref: #558-Scientific
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