LCMS Laboratory Manager 1

Pittsburgh, PA

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Type: Contract-to-Hire

Experience: 4

Category: Scientific & Clinical

Contractor Work Model: Onsite

Brand: Joulé

Job ID: 344109

Date Posted: 02/05/2026

Shortcut: http://jobs.systemone.com/8T9Zfx


Title: LCMS Lab Manager I
Location: Onsite, Pittsburgh, PA 15219
Type: 6-month contract to hire
Hours: 8AM-5PM
Start: Immediately

Overview:
Join a cutting-edge research core facilities team as a Research Specialist, you’ll focus primarily on LC/MS sample preparation and data acquisition—including protein, metabolite, and lipid isolation from tissues, cells, and biofluids. You will operate, monitor, and troubleshoot LC/MS instruments and transform acquired data into clear visualizations for the Principal Investigator. If you thrive in the lab and want your work to directly impact high-value research, we encourage you to apply!

Responsibilities

  • Majority of their time working on LC/MS sample preparation and data acquisition. Sample preparation methods will include protein, metabolite, and lipid isolation from various biological samples, including but not limited to tissue, cell pellets, urine, stool, and blood-derived samples.
  • Following isolation, will perform and monitor LC/MS instrumentation and data acquisition.
  • Responsible for analyzing and organizing the LC/MS data collected into various visualization software applications that will be sent to the primary investigator.
  • Additional primary duties will include monitoring, maintaining, and troubleshooting the LC/MS instrumentation.
  • Involved in completing basic laboratory functions, including maintaining laboratory equipment, organizing supplies, maintaining data backups, and performing weekly laboratory maintenance.
  • Must record all work completed in detail in an electronic lab notebook.
Requirements
  • Bachelor’s degree in chemistry, biochemistry or related area required
  • Minimum of 3 to 4 years of relevant experience in as liquid-extraction for small molecules and protein extraction and quantification
  • Experience working in Liquid Chromatography and Mass Spectrometry (LC/MS) or other analytical chemistry based sample preparation is preferred
  • Strong background in basic wet laboratory techniques, which will include sample preparation protein, metabolite, and lipid isolation from various biological samples, including but not limited to tissue, cell pellets, urine, stool, and blood-derived samples.

Physical Effort
Moderate physical effort required. May be required to sit, stand or move for several hours at a time. May be required to move objects up to 50 pounds with or without assistance of equipment.

System One, and its subsidiaries including Joulé, ALTA IT Services, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.


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