Title: Lead Integration Engineer
Location: Onsite, Pittsburgh, PA 15213
Type: Direct-Hire/Permanent
Hours: Standard business hours

Overview: Join a cutting-edge lab to discover novel therapeutics that are seeking a highly motivated Lead Engineer to support the integration, optimization, and operation of complex fluidic and instrumentation systems for advanced human-relevant experimental platforms. This role focuses on system-level design and implementation of fluid handling architectures, ensuring reliable, reproducible, and physiologically relevant operation across single- and multi-component platforms. The position will contribute to development of robust, scalable systems that integrate mechanical, fluidic, and control elements to support standardized experimental workflows.

Responsibilities:

• Design, develop, and optimize fluidic systems, including manifolds, tubing layouts, and pump-controlled flow networks
• Implement stable, leak-free circulation systems with controlled and reproducible flow profiles across experimental platforms
• Support development of physiologically relevant flow conditions, including continuous and directional flow regimes
• Integrate fluidic systems with broader experimental platforms, including device interfaces, instrumentation, and control systems
• Contribute to system-level architecture design, coordinating fluidic, mechanical, and sensing components
• Develop and implement control strategies for pumps, valves, and fluid routing systems
• Perform system testing, validation, and troubleshooting to ensure operational reliability and consistency
• Maintain detailed documentation of system configurations, standard operating procedures (SOPs), and performance validation
• Collaborate with multidisciplinary teams to align system functionality with experimental and operational requirements
• Contribute to improvement of system robustness, usability, and scalability for sustained and repeatable operation

Requirements:

• Bachelor’s degree in Mechanical Engineering, Electrical / Systems Engineering, or a related field
• Minimum of 3 years of relevant experience in fluid systems, instrumentation, or experimental platform development
• Experience with fluid handling systems, pumps, tubing, or flow control architectures
• Experience with system integration and hardware-based experimental platforms
• Strong analytical, troubleshooting, and problem-solving skills
• Ability to work effectively in multidisciplinary research and engineering environments

Preferred Qualifications

• Master’s or Ph.D. in a relevant engineering discipline
• Experience with microfluidics, perfusion systems, or biologically relevant flow systems
• Familiarity with control systems, sensors, and automated or semi-automated fluid handling platforms
• Experience with design and implementation of complex, multi-component systems
• Experience with data acquisition, monitoring systems, or system diagnostics
• Experience working at the interface of engineering and biological systems
• Experience in controlled or regulated laboratory environments

#M3
#LI-MD2
Ref: #558-Scientific