OMICS Laboratory Lead/Manager II
Pittsburgh, PA
Experience: 2
Category: Scientific & Clinical
Contractor Work Model: Onsite
Brand: Joulé
Job ID: 342852
Date Posted: 12/03/2025
Shortcut: http://jobs.systemone.com/5e3qqo
Title: OMICS Laboratory Manager II
Location: Onsite, Pittsburgh, PA 15219
Type: 6-month contract to hire
Hours: 8AM-5PM
Start: December
Overview:
Join as a Laboratory Manager II to monitor personnel and workflow in the area. Track and monitor QA/QC in conjunction with other laboratory leadership. Oversee laboratory throughput metrics and workflow optimization, ensuring balanced workloads, adherence to deadlines, and high data fidelity under time-sensitive conditions.
Responsibilities
- Manages daily laboratory operations of a division, department, function, or program, including conducting and overseeing quality assurance and quality control.
- Perform clinical testing in accordance with established SOPs. Maintain oversight of all clinical testing.
- Maintain clinical workflow for area to meet established quality and TAT, including technologist and bench schedule, status of cases (STAT, special request, etc).
- Maintain competency for all benches in area. Rotate regularly through clinical workflow.
- Be able to step in and help clinical work when necessary.
- Troubleshoot problematic cases, including when to repeat case and when to cancel testing.
- Act as point-person for communication with vendors regarding problems with instruments and/or software.
- Update SOPs, as needed, to maintain current accurate procedure documentation.
- With support and guidance from laboratory leadership and Medical Director, oversee supplemental validations and implementation of procedural changes.
- Write-up all supplemental validations and compile supporting data.
- Oversee training of technologists, including new hires and cross training of current technologists.
- Monitor and assess competency for all area technologists.
- Adhere to CAP and other regulatory agency regulations for competency assessment. Monitor Proficiency Testing for assays in area. Track all results for concordance and document as appropriate.
- Work with MGP QA and lab leadership and Medical Director as needed for preparation for inspections. Complete performance reviews for all area Molecular Genomic Specialists.
- Monitor and approve reagent/supply orders for area. Act as liaison for daily happenings in clinical workflow between technologists and laboratory leadership.
- Track area technologist indirect hours (MRS). Work with laboratory leadership including Medical Director for ideas for, validation of and implementation of development projects.
- Maintain track of technical and professional development, including but not limited to attendance at seminars/webinars and participation in educational programs and activities.
- Oversee sample triage, barcoding, and data integrity across all omics workflows.
- Ensure consistent application of CAP/CLIA-compliant procedures for sample tracking, storage, and LIMS documentation across genomic, proteomic, metabolomic, and lipidomic assays.
- Coordinate operation, scheduling, and maintenance of high-throughput automation platforms (Eppendorf, Tecan, Hamilton) and analytical instruments (Orbitrap Exploris, Stellar, SomaLogic, iScan).
- Provide mentorship and cross-training on multi-omics sample preparation, instrument workflows, and data tracking protocols to ensure consistency and scalability across teams.
- Lead validation and process harmonization for new assays across omics platforms.
- Collaborate with QA and regulatory teams to maintain CAP/CLIA readiness and audit documentation.
- Bachelor’s degree required
- Minimum of 3 years of relevant experience in a high-volume, complex clinical or research laboratory setting
- Advanced Excel skills
- Proficient in molecular biology techniques, including Illumina NGS Next-Generation Sequencing, PCR, library preparation, and barcoding
- Troubleshooting, mentoring and QC review experience
- Experience with laboratory automation and robotic systems, such as Hamilton instruments and automated liquid handlers
System One, and its subsidiaries including Joulé, ALTA IT Services, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.
System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.
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Ref: #558-Scientific
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