Purification & Analytics Scientist
Boston, Massachusetts
Experience: 8
Category: Scientific & Clinical
Contractor Work Model: Onsite
Brand: System One
Job ID: 381285
Date Posted: 10/08/2026
Shortcut: http://jobs.systemone.com/Gupqp1
Job Title: Purification & Analytics Scientist
Location: Boston, MA
Type: Contract to Hire
Compensation: $84.13
Work Model: Onsite
Hours: Standard business hours
Security Clearance: Not specified
Overview:
Join a growing U.S. biotechnology organization specializing in RNA medicine manufacturing. You'll be provide the specialist leadership on RNA purification and on the analytical strategy that determines whether a batch can be released.
Responsibilities
- Lead specialist in RNA purification and analytical strategy to determine batch release
- Manage purification unit operations: tangential flow filtration, membrane or chromatographic purification, including double-stranded RNA removal below 1% w/w and residual DNA below 10 ng/mg
- Develop and maintain the product quality attribute list per modality, mapped to quality-control measurement domains
- Define analytical target profiles for each attribute according to ICH Q2(R2) and Q14, including accuracy, precision, range, and specificity
- Rank and prioritize in-line, at-line, and off-line analytical technologies against established profiles with documented criteria
Requirements
- PhD or MS with equivalent experience in analytical chemistry, biochemistry, or bioprocess engineering
- Minimum of five years of experience in biologics or nucleic-acid purification and analytical development
- Ability to cover both purification process expertise and analytical expertise; candidates strong in only one area will leave a gap
System One, and its subsidiaries including Joulé and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.
System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.
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Ref: #558-Scientific
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⚠️ Protecting Job Seekers from Identity Scams
At System One, your privacy and security are important to us. As job-related scams continue to target job seekers, we want to help you recognize and avoid common recruitment fraud. Identity theft scams often involve individuals, also known as "scammers," posing as recruiters or employers to obtain sensitive personal information, such as Social Security numbers, bank account details, or copies of driver’s licenses, with the goal of stealing identities, accessing financial accounts, or creating fraudulent accounts in a victim’s name.