Software Engineer — Manufacturing Control & User Interface

Boston, Massachusetts

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Type: Contract-to-Hire

Experience: 5

Category: Scientific & Clinical

Contractor Work Model: Onsite

Brand: System One

Job ID: 381284

Date Posted: 10/08/2026

Shortcut: http://jobs.systemone.com/weQ7UY


Job Title: Software Engineer — Manufacturing Control & User Interface
Location: Boston, MA
Type: Contract to Hire
Compensation: $76.92
Work Model: Onsite – onsite
Hours: Standard business hours
Security Clearance: Not specified

Overview:
Join a growing U.S. biotechnology organization specializing in RNA medicine manufacturing. You'll own the software and controls that bring complex automated equipment to life—making each system fully operable, integrated, traceable, and audit-ready.

Responsibilities

  • Own the software that makes the machine operable and auditable.
  • Manage the system-level state machine governing process sequencing across all six subsystems, including interlocks, alarms, and fault-recovery logic.
  • Develop and maintain the dual user interface: an on-site interface constrained to a single touchscreen, and a remote interface supporting full off-site process execution and lot disposition.
  • Ensure version-controlled implementation traceable to the architecture document, hardware-in-the-loop bench testing, and formal verification of the state machine and interfaces.
  • Support the integration and validation of data interfaces between manufacturing and analytics systems.

Requirements

  • BS or MS in computer science, software engineering, or an engineering discipline with a strong software track.
  • At least five years building full-stack software that controls or records physical processes — instrument control, industrial automation, laboratory informatics, or manufacturing execution.
  • Strong in at least one of Python, C#/.NET, or C++ for instrument software, plus modern web front-end for the operator and remote interfaces.
  • Fluency and ability to strategically use GenAI coding platforms.
  • Knowledge of state machines, real-time constraints, device communication protocols, and structured data modeling.
  • Hands-on experience delivering software and strong exposure to regulated environments, specifically 21 CFR Part 11, GAMP 5, computer system validation, audit trails, and electronic signatures.

**System One, and its subsidiaries including Joulé and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

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Ref: #558-Scientific

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