Scientist, Antibody Engineering
Rockville, MD
Experience: 0
Category: Scientific & Clinical
Contractor Work Model: Onsite
Brand: Joulé
Compensation Range: 30.00 - 40.00 Per Hour
Job ID: 344468
Date Posted: 02/04/2026
Shortcut: http://jobs.systemone.com/1aF6cI
Job Title: Scientist, Antibody Engineering
Location: Rockville, MD (Onsite)
Hours/Schedule: Monday–Friday, core hours 8:00 AM – 5:00 PM (some flexibility)
Compensation: $32-$40/hour
Type: Contract (6 months) with potential for extension
Overview
Leading biotechnology organization is seeking a Scientist, Antibody Engineering to support early-stage biologics discovery programs. This role is highly hands-on and molecular biology-driven, with a strong emphasis on antibody DNA generation, expression, and functional evaluation. The Scientist will play a key role in advancing antibody candidates through discovery with a clear understanding of how their work contributes to the broader drug development lifecycle.
Responsibilities
- Design, generate, and engineer antibody DNA constructs using core molecular biology techniques
- Perform PCR, plasmid preparation, cloning, mutagenesis, and sequence analysis to support antibody generation workflows
- Express recombinant antibodies and evaluate performance using ELISA and related protein immunoassays
- Assess antibody function, binding, and developability, focusing on performance-driven evaluation rather than purely descriptive characterization
- Support antibody optimization efforts across multiple formats (e.g., monoclonal, bispecific)
- Interpret experimental data within the context of antibody discovery and early drug development goals
- Collaborate closely with cross-functional discovery scientists to advance antibody programs
- Document experimental methods, results, and conclusions in accordance with internal research standards
Requirements
- Bachelor’s degree in a life science with 2–5 years of relevant experience OR; Master’s degree in a life science with 1–3 years of relevant experience
- Strong, hands-on experience in molecular biology–driven antibody engineering, including: PCR, Plasmid DNA preparation, Molecular cloning and mutagenesis, Sequence analysis
- Proven experience performing and interpreting ELISA and protein immunoassays for antibody evaluation
- Experience with plasmid and sequence analysis software (e.g., SnapGene) and data analysis tools (e.g., GraphPad Prism, Excel)
- Demonstrated understanding of how antibody engineering work fits into the broader drug discovery and development lifecycle
- Strong collaboration, documentation, and problem-solving skills in a fast-paced research environment
- Must be legally authorized to work in the United States for any employer
Benefits
System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan.
#M-3
#LI-MM1
#DI-
Ref: #558-Scientific
-
Senior Scientist I - Computational Biologist
Rockville, MD
Job Title: Senior Scientist, Computational Biology- Antibody Engineering Location: Rockville, MD (100% Onsite) Hours/Schedule: Monday–Friday, 9:00 AM – 5:00 PM Compensation: $45.00 – $70.00/hour Type: Contract (6 months, extension possible but not guar...
Date Posted: 02/04/2026 Recommended
-
Scientist
Quincy, MA
Title: Food Scientist Location: Quincy MA Schedule: M-F 8-5 onsite daily Will accept relocation candidates Salary: up to $112k Start ASAP Education: BS/MS/PhD in Food Science/Engineering/related science or engineering field Requirements: 4+ years of ex...
Date Posted: 12/16/2025 Recommended
-
Senior Safety Verification and Validation Engineer
Bellevue, Washington
Job Title: Senior Safety Verification and Validation Engineer Type: Contract (12-months) Contractor Work Model: Remote About the Role: As a Senior Safety V&V Engineer, you will be instrumental in verifying and validating safety assessment models and so...
Date Posted: 02/12/2026 Recommended
-
Sales Engineer - Nuclear Manufacturing
Chattanooga, TN
Job Title: Sales Engineer – Nuclear Manufacturing Location: Chattanooga, TN Experience Preferred: 10+ Years Reports To: Vice President of Sales Company Overview: Join a highly respected precision manufacturing firm based in Chattanooga, TN, specializin...
Date Posted: 12/29/2025 Recommended
-
Quality Engineer
Orangeburg, NY
Title: Quality Engineer Location: Orangeburg, NY area Start Date: ASAP! Duration: 6 Month Contract (runs through at least the end of July) Hours: Mon-Fri; 8 hour days (5 days a week in office) *flexible start time anywhere between 7am-9am Rate: $38-$43...
Date Posted: 01/21/2026 Recommended
-
Fleet Risk Lead Engineer
Lake Mary, FL
Fleet Risk Lead Engineer Lake Mary, FL Type: Direct Hire Contractor Work Model: Onsite SUMMARY The Fleet Risk Senior Engineer supports the development and execution of the Fleet Risk Management Program, which identifies and mitigates emerging risks wit...
Date Posted: 12/19/2025 Recommended
-
Electrical Engineer
Lenexa, KS
Job Title: Electrical Engineer Location: Lenexa, KS Job Type: Contract-to-Hire Work Model: Onsite (4–5 days per week) Conversion Salary Range: $90,000 – $115,000 (flexible based on experience) Position Overview We are seeking a high-level Electrical En...
Date Posted: 02/13/2026 Recommended
-
Drainage Engineer
Guaynabo, Puerto Rico
Job Title: Drainage Engineer Location: Guaynabo, Puerto Rico Type: Direct Hire Compensation: $72000 - $93000 annually Contractor Work Model: Onsite System One is actively seeking a Drainage Engineer for a direct hire opportunity with a client in Guayna...
Date Posted: 01/20/2026 Recommended
-
Engineer (Mechanical, Electrical, or Plumbing)
Norfolk, Virginia
Position Title: Engineer [ Mechanical, Elelctrical Or Plumbing) Position Location: Baltimore, MD and Norfolk , VA Duration – Direct Hire Responsibilities: As a fully competent Registered Professional Engineer, performs work involving the application of...
Date Posted: 12/08/2025 Recommended
-
Senior Designer
Baltimore, MD
Position Title: Senior Designer Position Location: Baltimore, MD and Norfolk , VA Duration – Direct Hire Responsibilities: Performs work involving the application of all conventional aspects of engineering to the functional area of the assignment. Exer...
Date Posted: 12/08/2025 Recommended
-
Road Move Engineer
Phoenix, AZ
Mountain Ltd. has an opening for Road Move Engineer in the Phoenix, AZ area! Since 1979, Mountain Ltd has successfully created and supported turnkey engineering solutions for traditional and wireless telecom providers across the United States. We are a...
Date Posted: 01/05/2026 Recommended
-
Intern, Manufacturing Operations & Continuous Improvement
York, Pennsylvania
Job Title: Intern, Manufacturing Operations & Continuous Improvement Location: York, Pennsylvania Type: Contract Compensation: $23.40 hourly Contractor Work Model: Onsite Projected Hire Date: May 2026 Projected End Date: August 2026 Position Overview: ...
Date Posted: 11/20/2025 Recommended
-
Senior Civil/Structural Engineer
Lake Mary, FL
Job Title: Senior Civil/Structural Engineer Location: Lake Mary, FL Type: Direct Hire Compensation: $115000 - $135000 annually Overview A leading engineering organization is seeking a highly skilled Senior Civil and Structural Engineer to take ownershi...
Date Posted: 11/19/2025 Recommended
-
LC-MS Research Scientist
Pittsburgh, PA
Title: LC-MS Research Scientist Location: Onsite, Pittsburgh, PA 15213 Type: 6-month contract to hire Hours: 8AM-5PM Start: January Overview: Join as a Research Scientist to will be responsible for developing, optimizing, and validating LC-MS assays to...
Date Posted: 01/21/2026 Recommended
-
LabView Test Engineer
Batesburg-Leesville, South Carolina
Job Title: LabView Test Engineer Location: Batesburg-Leesville, South Carolina Type: Contract LabView Test Engineer Accountabilities: Ensure the implementation of assigned actions as per the manufacturing action plan (i.e., audit, failure analysis, imp...
Date Posted: 12/18/2025 Recommended
-
Resident Engineer - Nuclear
Loveland, Colorado
Resident Engineer Location: Onsite in Loveland, CO Pay Rate: $50–$80/hour Position Type: Contract (via System One) System One is seeking a highly motivated Nuclear Island Resident Engineer to support supplier activities on-site at James Fisher Technolo...
Date Posted: 01/09/2026 Recommended
-
Senior Mechanical Engineer (Heat Mass Balance)
Charlotte, NC
Job Title: Senior Mechanical Engineer (Heat Mass Balance) Location: Charlotte, NC Type: Contract to direct hire Compensation: $75/hr (+/-) DOE Contractor Work Model: Onsite Hours: 40 hours/week Start Date: ASAP Duration: Long Term System One is current...
Date Posted: 01/15/2026 Recommended
-
EMC Laboratory Supervisor
Atlanta , Georgia
Job Title: EMC LABORATORY SUPERVISOR Location: Knoxville, TN (Relocation Required) Work Model: Onsite System One is actively recruiting for an EMC LABORATORY SUPERVISOR for a permanent position located in Knoxville, Tennessee. This position will suppor...
Date Posted: 01/12/2026 Recommended
-
EMC Laboratory Supervisor
Shelby, North Carolina
Job Title: EMC LABORATORY SUPERVISOR Location: Knoxville, TN (Relocation Required) Work Model: Onsite System One is actively recruiting for an EMC LABORATORY SUPERVISOR for a permanent position located in Knoxville, Tennessee. This position will suppor...
Date Posted: 01/12/2026 Recommended
-
EMC Laboratory Supervisor
Knoxville, TN
System One is actively seeking an EMC LABORATORY SUPERVISOR for a permanent position located in Knoxville, Tennessee. This position will support our client, a leading nuclear engineering services company headquartered in Knoxville, Tennessee with a wor...
Date Posted: 01/29/2026 Recommended
-
Environmental and Seismic Engineer
Oak Ridge, Tennessee
Environmental & Seismic Engineer – Oak Ridge, TN (Onsite) Type: Direct Hire Work Model: Onsite (Relocation assistance not provided) System One is seeking an experienced Environmental and Seismic Engineer to support nuclear facility programs in Oak Ridg...
Date Posted: 02/12/2026 Recommended
-
Mechanical Engineer (Structural)
Tulsa, OK
Mechanical Engineer (Structural emphasis) This is an exciting opportunity for a Mechanical or Civil Engineer to join a fast-growing company. We are seeking an inspired individual looking to make a significant impact in a challenging and rewarding field...
Date Posted: 02/03/2026 Recommended
-
Civil/Structural Engineer III
Lake Mary, FL
Job Title: Civil/Structural Engineer III Location: Lake Mary, FL Type: Direct Hire Compensation: $100000 - $125000 annually Work Model: Onsite Engineer III, Civil & Structural Overview A leading engineering organization is seeking an experienced Engine...
Date Posted: 11/19/2025 Recommended
-
Senior Project Engineer
Cambridge, Massachusetts
Job Title: Senior Project Engineer Location: Cambridge, Massachusetts Type: Direct Hire Compensation: $160000 - $210000 annually Contractor Work Model: Hybrid System One is currently seeking a Senior Project Engineer on a direct hire position located i...
Date Posted: 02/03/2026 Recommended
-
Traffic Engineer PE
Houston, Texas
Job Title: Traffic Engineer (PE) Location: Houston, Texas Type: Direct Hire Contractor Work Model: Onsite System One is assisting a client in hiring a Traffic Engineer PE. The ideal candidate will demonstrate expertise and strong relationships with TXD...
Date Posted: 02/06/2026 Recommended
-
Architect - Project
Richmond, Virginia
Project Architect Richmond, VA | Full-Time | Hybrid Work Schedule Available Are you an experienced architect looking for an opportunity to lead exciting, complex projects while mentoring the next generation of designers? We’re seeking a Project Archite...
Date Posted: 02/09/2026 Recommended
-
Structural - Project Engineer
Alexandria, Virginia
Structural Project Engineer Alexandria, VA | Full-Time | Hybrid Work Schedule Available Are you a creative and detail-oriented engineer who enjoys solving complex design challenges? We’re looking for a Structural Project Engineer to join a dynamic, emp...
Date Posted: 02/09/2026 Recommended
-
Senior Controls Automation Engineer
Cannonsburg, Pennsylvania
Job Title: Senior Controls Automation Engineer Location: Cannonsburg, Pennsylvania Type: Direct Hire Compensation: $140000 - $155000 annually Contractor Work Model: Onsite System One is currently seeking a Senior Automation Engineer on a direct hire po...
Date Posted: 12/05/2025 Recommended
-
Electrical Department Manager
Pittsburgh, PA
Electrical Engineering Department Manager Pittsburgh, PA System One is seeking a Lead Electrical Engineer to provide technical support and oversight for heavy industrial electrical projects in the Pennsylvania Region. This is a hybrid position. It is p...
Date Posted: 01/20/2026 Recommended
-
Asst Engineering Technician - Electrical Substation Drafter
Cary, North Carolina
Job Title: Asst Engineering Technician - Electrical Substation Drafter Location: Cary, North Carolina Type: Contract Compensation: $28 - $32.5 hourly Contractor Work Model: Onsite Hours: Add the job’s scheduled days and times (delete if not needed) Sec...
Date Posted: 02/12/2026 Recommended