LC-MS Research Scientist
Pittsburgh, PA
Experience: 4
Category: Scientific & Clinical
Contractor Work Model: Onsite
Brand: Joulé
Job ID: 344111
Date Posted: 01/21/2026
Shortcut: http://jobs.systemone.com/CJCmzs
Title: LC-MS Research Scientist
Location: Onsite, Pittsburgh, PA 15213
Type: 6-month contract to hire
Hours: 8AM-5PM
Start: January
Overview:
Join as a Research Scientist to
will be responsible for developing, optimizing, and validating LC-MS assays to support research and development efforts. This role involves method development, sample preparation, data acquisition, data analysis, troubleshooting, instrument maintenance, and documentation in a regulated or research environment. This role will be involved in collaborative efforts and provide scientific leadership in LCMS-based analytical projects.
Responsibilities
- Involved in applying and maintaining complex LCMS (liquid chromatography and mass spectrometry) instrumentation.
- Managing collaborative research projects, while developing and validating LC-MS methods (quantitative and/or qualitative) for small molecules, peptides, proteins, metabolites, or other analytes.
- Design experiments for project and method development, operate and maintain mass spectrometers (e.g., triple quadrupole, Orbitrap, Q-TOF) and LC instrumentation, process and analyze mass spec data using relevant software
- Interpret data scientifically and ensure quality control, write and review method standard operating procedures and protocols, and present data.
- Maintain a safe laboratory environment, comply with safety and regulatory policies, and manage laboratory supplies and inventory.
- Contribute to continuous improvement and innovation in bioanalytical techniques, instrumentation, and workflows with the opportunity to train junior staff / scientists in LCMS techniques, good laboratory practices, and data analysis.
- MUST have PhD degree in chemistry, biochemistry, or related scientific discipline with relevant postdoctoral or industrial experience.
- Must have expertise in instrument maintenance, sample preparation and method development across multiple platforms including metabolomics, lipidomic and proteomics
- A strong work ethic, communication skills, ability to troubleshoot, be detail orientated and organized, and be able to manage multiple interdisciplinary projects and timelines with minimal supervision
Physical Effort
Moderate physical effort required. May be required to sit, stand or move for several hours at a time. May be required to move objects up to 50 pounds with or without assistance of equipment.
System One, and its subsidiaries including Joulé, ALTA IT Services, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.
System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.
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